Crossword Clue: Islam's second-holiest city
Here's the answer to the Islam's second-holiest city crossword clue, with an explanation and where it has appeared.
Definition & answer: MEDINA
The answer to "Islam's second-holiest city" is MEDINA. Medina is a 6-letter word made up of 3 vowels and 3 consonants, beginning with M and ending with A. In a crossword grid it occupies a 6-square slot, and each of its letters also forms part of a word crossing it — so even if the clue stumps you, the crossing entries will usually hand you enough letters to fill it in.
Origin & meaning
Medina is the second-holiest city in Islam and the site of Muhammad's tomb. The Prophet migrated here from Mecca in 622, marking the start of the Islamic calendar. The green-domed Prophet's Mosque is a major pilgrimage site.
Common usage
Medina turns up frequently in crosswords precisely because of that letter mix. Short, vowel-friendly words like MEDINA are a constructor's best friend: they interlock cleanly with longer entries and help a grid come together without awkward letter clashes. When you see a 6-letter slot and already have a crossing letter or two, MEDINA is often quick to confirm — especially once the M or A is in place.
Crossword trivia
Because it is only 6 letters long, MEDINA appears far more often in daily mini and themed puzzles than longer, more obscure words. Regular solvers come to recognize it on sight, and it is exactly the kind of entry worth committing to memory: the more common short words you know cold, the faster your solve times become.
Stuck on this clue?
If "Islam's second-holiest city" has you stuck, don't force it — jump to the clues crossing this slot instead. Filling in even one or two intersecting letters usually makes MEDINA obvious. That crossing-first approach is the single most useful habit for improving at crosswords, and it works on everything from the quick daily Mini to a full Sunday grid.
This clue in different puzzles
Setters vary how they clue MEDINA — sometimes with a straight dictionary definition, sometimes with wordplay, a pun, or a fill-in-the-blank — but the answer itself stays the same. Learning to spot the answer behind the disguise is a core crossword skill.
Example sentences
- "I had the crossing letters, so writing MEDINA into the grid took no time at all."
- "Medina is the kind of answer that clicks the moment you spot one letter."
- "Seeing 'Islam's second-holiest city' in the clue list, an experienced solver pencils in MEDINA almost immediately."
- "Once the M was confirmed by the crossing word, MEDINA was the only entry that fit."